How are PIEDs used?
PIEDs are commonly swallowed, injected under the skin, or rubbed onto the skin.8
People who use anabolic steroids may practice:
- Stacking: Taking different types of steroids at specific doses, to achieve a specific effect.
- Cycling: Taking periods on and off steroid use, to avoid side effects of use.
- Blasting and cruising: Taking a higher amount, then lower amount of steroids, to avoid losing muscle or withdrawal symptoms.9
There is little evidence that these approaches work. Taking more than one steroid at a time and continuous use, increases the risk of harm.9
Effects of PIEDs
Use of any drug can have risks. It’s important to be careful when taking any type of drug.
PIEDs affect everyone differently, based on:
- size, weight and health
- whether the person is used to taking it
- whether other drugs are taken around the same time
- the amount taken
- the strength of the drug (varies from batch to batch)
- method of use (oral vs injection)
- The type of PIEDs used
Effects may include:
- acne
- hair loss
- mood and behaviour changes
- joint problems
- high blood pressure
- increased tiredness
- water retention
- numbness of hands and feet
- heart and kidney problems
- liver damage
- changes in sex drive
- shrinking testicles and prostate problems
- changes in menstrual cycle
- developing or shrinking breast tissue
- stunted growth for young people9,4,10
If PIEDs are injected, there is an increased risk of:
- tetanus
- infection
- vein or skin damage.6
If sharing needles with other people, there is an increased risk of:
- Hepatitis B
- Hepatitis C
- HIV.8
Many synthetic peptide hormones are experimental or not yet approved for human use, which can cause unpredictable effects.4
Overdose
If you take a large amount, of PIEDs, or have a strong batch, you could overdose. Overdose risk, as well as symptoms, will depend on the type of PIED used.
Call an ambulance straight away by dialling triple zero (000) if you, or someone else, has any of the following symptoms (Emergency services are there to help and can provide instructions over the phone):
- sweating
- paleness
- fast heart rate
- feeling faint
- trembling
- blurred vision
- confusion
- seizures.5
Long-term effects
Regular use of PIEDS may eventually cause:
- heart damage/disease
- liver or kidney damage/disease
- fertility problems
- infection
- muscle damage
- mental health conditions.5-7
PIEDs and mental health
People who use PIEDS may experience muscle dissatisfaction, general lack of interest, anxiety, depression, fatigue, irritability, and aggression. PIEDs use has also been linked to eating disorders and body and muscle dysmorphia.1
Tolerance and dependence
People can develop a psychological dependence to PIEDs, due it effects on physique and strength, that can result in increased self-esteem and confidence. Some people can also develop a physical tolerance to PIEDs.10
Mixing PIEDs with other drugs
Anabolic steroids + stimulants (cocaine/amphetamine): increases risk of heart disease, high blood pressure, aggression, and sleep problems.7
More on Polydrug use
Polydrug use is a term for the use of more than one drug or type of drug at the same time or one after another. Polydrug use can involve both illicit drugs and legal substances, such as alcohol and medications.
Reducing harm
There are ways you can reduce the risk of harm when taking PIEDs:
- Avoid using high doses and take regular breaks to reduce side effects
- Never inject directly into biceps, calf muscles or pecs
- Avoid injecting into same area of body
- Use sterile injecting equipment
- Don’t share or reuse injecting equipment and dispose of used equipment safely
- Consider getting regular liver and kidney function tests.9,12
Withdrawal
Giving up PIEDs after using for a long time is challenging because the body has to get used to functioning without them.
Withdrawal symptoms and times vary depending on PIED type, but often should settle down after a few days and mostly disappear after 2 weeks.13
Symptoms may include:
- low mood
- fatigue and low energy
- trouble sleeping
- decreased appetite
- decreased or loss of sex drive5
Getting help
If your use of PIEDs is affecting your health, family, relationships, work, school, financial or other life situations, or you’re concerned about a loved one, you can find help and support.
Call the National Alcohol and Other Drug Hotline on 1800 250 015 for free and confidential advice, information and counselling about alcohol and other drugs
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Find out moreIt’s illegal to use, possess, manufacture, supply, or import steroids without a prescription or medical licence. The penalties vary for every Australian state and territory.14
Medical practitioners can only prescribe steroids for legitimate medical reasons.14
Many PIEDs, like steroids, are banned in competitive sport. Testing positive can result in fines, suspensions, or lifetime bans.15
- The Australian Needle and Syringe Program survey found that the third most commonly reported drug last injected nationally in 2022 was performance and image enhancing drugs (PIEDs).2
- The rate of injecting PIEDs also increased significantly from 4% in 2018 to 7% in 2022.2
- Larance B Degenhardt L Dillon P Copeland J. Use of performance and image enhancing drugs among men: A review. Sydney National Drug and Alcohol Research Centre; 2005 [19.06.2024].
- Heard S, Zolala F, Maher L,. Australian NSP Survey National Data Report 2018-2022: Prevalence of HIV, HCV and injecting and sexual behaviour among NSP attendees: Kirby Institute, UNSW Sydney; 2023 [19.06.2024].
- Velloso CP. Regulation of muscle mass by growth hormone and IGF-I. British Journal of Pharmacology [Internet]. 2008 [19.06.2024].
- Australian Crime Commission. Organised Crime and Drugs in Sport: Australian Crime Commission; 2013 [19.06.2024].
- van de Ven K, Eu B, Jackson E, Han E, Gouda N, Simmonds P, et al. GP guide to harm minimisation for patients using non-prescribed anabolic-androgenic steroids (AAS) and other performance and image enhancing drugs (PIEDs). Sydney: Sydney North Health Network [Internet]. 2020 [19.06.2024].
- Sagoe D, McVeigh J, Bjørnebekk A, Essilfie M-S, Andreassen CS, Pallesen S. Polypharmacy among anabolic-androgenic steroid users: a descriptive metasynthesis. Substance Abuse Treatment, Prevention, and Policy [Internet]. 2015 [19.06.2024].
- Zahnow R, McVeigh J, Bates G, Winstock AR. Motives and Correlates of Anabolic-Androgenic Steroid Use With Stimulant Polypharmacy. Contemporary Drug Problems [Internet]. 2020 [19.06.2024].
- van de Ven K, Zahnow R, McVeigh J, Winstock A. The modes of administration of anabolic-androgenic steroid (AAS) users: are non-injecting people who use steroids overlooked? Drugs: Education, Prevention and Policy [Internet]. 2020 [19.06.2024]; 27(2):[131-5 pp.].
- Rowe R, Berger I, Copeland J. “No pain, no gainz”? Performance and image-enhancing drugs, health effects and information seeking. Drugs: Education, Prevention and Policy [Internet]. 2017 [19.06.2024].
- Larance B Degenhardt L Dillon P Copeland J. Rapid assessment of performance and image enhancing drugs (PIEDs) in New South Wales: Feasibility study: National Drug and Alcohol Research Centre 2005 [19.06.2024].
- Tucker JA, Darke, S, Lappin, J, Farrell, M. The Clinicians Guide to Illicit Drugs and Health: Silverback Publishing; 2019 [17.01.2024].
- Hi-ground. Steroids [19.06.2024].
- Pascual J, Royuela A, Galeano C, Crespo M, Zamora J. Very early steroid withdrawal or complete avoidance for kidney transplant recipients: a systematic review *. Nephrology Dialysis Transplantation [Internet]. 2012 [19.06.2024].
- Australian Government Department of Health. Performance and Image Enhancing Drugs: What you need to know [19.06.2024].
- Therapeutic Goods Administration (TGA). Performance and image enhancing drugs 2019 [19.06.2024].