DMT

DMT

Last published: September 23, 2024

What is DMT

DMT (Dimethyltryptamine) is a strong psychedelic drug, which means it can affect all the senses, altering a person’s thinking, sense of time and emotions. Psychedelics can cause a person to hallucinate, seeing or hearing things that do not exist or are distorted.1,2

DMT is structurally similar to psilocybin (magic mushrooms) and is known to produce short acting and intense visual hallucinations.2

What does DMT look like?

DMT is found in a variety of plants and animals, and is the psychoactive ingredient in the drug ayahuasca.3 In ayahuasca, a plant containing DMT is boiled together with a plant containing a monoamine oxidase inhibitor (MAOI) such as harmaline, and the mixture is drunk.4

When produced synthetically DMT is a white crystalline powder.3

Other names

Dimitri, Deems The spirit molecule, Changa, Fantasia, the glory, the sacrament

How is DMT used?

DMT can be:

  • vaporised or smoked in a pipe
  • drunk as part of an ayahuasca brew
  • snorted
  • injected.5

Effects of DMT

Use of any drug can have risks. It’s important to be careful when taking any type of drug.

Psychedelics affect everyone differently, based on:

  • size, weight and health
  • whether the person is used to taking it
  • whether other drugs are taken around the same time
  • the amount taken
  • the strength of the drug (varies from batch to batch)
  • environment (where the drug is taken).

DMT is most commonly smoked in Australia, with effects commencing almost straight away and finishing after around 30 minutes.5 Effects may include:

  • a ‘rush’
  • feeling happy and excited
  • changes in mood
  • increased sensitivity to bodily sensations (body aches, tingles, feelings of pain and pleasure, warmth and fatigue)
  • increased heart rate and blood pressure
  • small pupils
  • anxiety and confusion
  • intense visual hallucinations
  • dissociation.5,6

Impact of mood and environment

Drugs that affect a person’s mental state (psychoactive drugs) can also have varied effects depending on a person’s mood (often called the ‘set’) or the environment they are in (the ‘setting’):

  • Set: a person’s state of mind, previous encounters with psychedelic drugs, and expectations of what’s going to happen. For example, feelings of stress or anxiety before using DMT may result in an unpleasant experience (bad trip).7
  • Setting: the environment in which someone consumes a psychedelic drug – whether it’s known and familiar, who they’re with, if they’re indoors or outdoors, the type of music and light. For example, using DMT in a calm, quiet and relaxed environment can lead to, or contribute to, a pleasant experience but being in a noisy, crowded place may result in a negative experience.7
  • Being in a good state of mind, with trusted friends and a safe environment before taking DMT reduces the risk of having a ‘bad’ trip.

Overdose

If someone takes a large amount, the negative effects of DMT are more likely. Call an ambulance straight away by dialling triple zero (000) if you or someone else has any of these symptoms:

  • vomiting
  • inability to move
  • intense anxiety and confusion
  • overwhelming fear and paranoia
  • psychosis
  • increased risk-taking6,8,9

Ambulance officers do not need to involve the police.

Bad trips

Some people may have negative experiences taking any psychedelics, or experiences they find challenging. This can happen even if a person takes a moderate dose. During a bad trip, you may experience frightening or confronting hallucinations, and feelings of anxiety, confusion, fear and paranoia.6,8,9

Coming down

There is little data on the comedown effects of DMT, but anecdotal user reports suggest that you may experience:

  • feeling a bit confused and unable to think clearly
  • trouble concentrating
  • feeling anxious or panicked
  • feeling disconnected with your body
  • racing thoughts or realisations
  • trouble sleeping.10,11

Long-term effects

The most common long-term effect of psychedelic use is ‘flashbacks’. Flashbacks are a re-experience of the drug and can occur days, weeks, months and even years later after using.6,8

Flashbacks can be triggered by the use of other drugs or by stress, fatigue or physical exercise. The flashback experience can range from being pleasant to causing severe feelings of anxiety. They are usually visual and last for a minute or two.6,8

There have been no reports of toxic effects from the long-term use of DMT, aside from concerns regarding the cardiovascular impact of increased heart rate and blood pressure.1

DMT and mental health

For people with a history of mental health concerns, or a current condition, DMT can worsen symptoms in some cases.9,11,12

Tolerance and dependence

Reports suggest that DMT does not produce any tolerance, and there is low potential for dependence to occur.13

Mixing DMT with other drugs

Mixing DMT with other drugs can have unpredictable effects and increase the risk of harm.

  • DMT and Tramadol: may cause seizures.
  • DMT and Cannabis: risk of anxiety, paranoia, panic, psychosis.
  • DMT and ice/speed/cocaine: can increase risk of anxiety & negative thought loops, leading to a negative experience.9,12,14

More on Polydrug use

Polydrug use is a term for the use of more than one drug or type of drug at the same time or one after another. Polydrug use can involve both illicit drugs and legal substances, such as alcohol and medications.

READ MORE

Reducing Harm

There are ways you can reduce the risk of harm when taking DMT:

  • Do your research first around the correct form of DMT to use, as well as what is a suitable dose and the safest method of use.
  • Start with a lower dose until you know how the drug affects you personally. It will be different for everyone.
  • Use around people you trust in a comfortable and safe environment
  • Find a quiet relaxing place where you can sit or lie down if needed as the experience can be overwhelming and disorientating.
  • Consider having a person to 'trip sit'. A person who remains sober and that can help out if needed.
  • If you’re not in a good frame of mind, consider whether it is the right time to take DMT.9,15

Withdrawal

According to user reports, DMT does not cause any physical withdrawal symptoms. However, some people who use DMT may feel like they need it again for ‘insight’ or to have another meaningful experience.11

Getting Help

If your use of DMT is affecting your health, family, relationships, work, school, financial or other life situations, or you’re concerned about a loved one, you can find help and support.

If you're looking for other information or support options, send us an email at druginfo@adf.org.au

Use of DMT is against the law. Federal and state laws provide penalties for possessing, using, making, selling, importing or exporting, or driving under the influence of methamphetamine.16

  1. Carbonaro T Gatch M. Neuropharmacology of N,N-Dimethyltryptamine. Brain Research Bulletin [Internet]. 2016 [27.05.2024]; 126.
  2. Nichols D. Psychedelics. Pharmacological Reviews [Internet]. 2016 [cited [27.05.2024; 68:[264–355 pp.].
  3. National Institute on Drug Abuse. Hallucinogen Drug Facts 2019 [27.05.2024].
  4. Vazquez G Zarate C Brietzke E. Ketamine for Treatment-Resistant Depression: neurobiology and applications 2020 [27.05.2024].
  5. Cakic V Potkonyak J Marshall A. Dimethyltryptamine (DMT): subjective effects and patterns of use among Australian recreational users. Drug and Alcohol Dependence [Internet]. 2010 [27.05.2024]; 111:[30-7 pp.].
  6. Brands B, Sproule B, Marshman J. Drugs and Drug Abuse. Toronto: Addiction Research Foundation; 1998 [08.05.2024].
  7. Nutt D. Drugs without the hot air : making sense of legal and illegal drugs. Cambridge: UIT Cambridge Ltd; 2012 [17.01.2024].
  8. Campbell A.The Australian Illicit Drug Guide: Every Person's Guide to Illicit Drugs--Their Use, Effects and History, Treatment Options and Legal Penalties: Black Inc; 2001 [08.05.2024].
  9. Harm Reduction Victoria. DMT n.d. [27.05.2024].
  10. healthline.DMT Side Effects to Know About 2019 [28.05.2024].
  11. The Level. DMT [28.05.2024].
  12. Psychonaut Wiki. DMT 2022 [27.05.2024].
  13. Winstock A Kaar S Borschmann R. Dimethyltryptamine (DMT): prevalence, user characteristics and abuse liability in a large global sample. Journal of Psychopharmacolgy [Internet]. 2014 [28.05.2024]; 28(1):[49–54 pp.].
  14. Tripsit Harm Reduction Thorugh Education.Drug Combinations n.d. [27.05.2024].
  15. Drug Science. DMT (N,N-Dimethyltryptamine) 2021 [27.05.2024].
  16. Therapeutic Goods Administration (TGA). Scheduling delegate's final decisions, July 2016 4.4 N,N-Dimethyltryptamine 2016 [27.05.2024].

Explore psychedelics on the Drug Wheel

Drug Wheel psychedelics

Effects

changes in mood , dilated pupils , dissociation , euphoria , increased rectal temperature , increased sensitivity to bodily sensations , intense visual hallucination , rush of euphoria

AKA

Changa , Dimitri , Fantasia , The spirit molecule